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June 2020 - Tothova Lab welcomes Dylan MillsonWe are very happy to welcome Dylan Millson who is joining our team as a new research associate. Dylan grew up in North Carolina and graduated from Williams College in 2020 with degrees in chemistry and biology. He was a four-year member of Williams wrestling team. Dylan completed his undergraduate thesis in the lab of Prof. Ben Thuronyi, where he developed a modular DNA toolkit to enable fluorescent proteins to form phase condensates in E. coli. In the Tothova lab, he aims to study genetic and epigenetic aberrations that contribute to myeloid malignancies. When he isn't in the lab, Dylan enjoys reading, lifting weights, and playing electric bass.
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March 2020 - Tothova Lab welcomes Will DoyleWe are very excited to welcome Will Doyle as a new research associate in the Tothova lab. Will grew up in Arlington, MA and graduated from Williams College in 2019 with a major in biology. For his undergraduate thesis in the lab of Prof. Lois Banta, he studied the connected roles of a plant defense hormone and the bacterial type VI secretion system in Agrobacterium tumefaciens infection. Will is joining the Tothova Lab to contribute to the understanding of epigenetic dysregulation in leukemia development. Outside of the lab, he enjoys playing jazz trombone, studying languages, and baking bread.
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February 2020 - The lab has moved to DFCI!We are very excited to be unpacking boxes in our second new home at the Dana-Farber. Come visit us in Mayer 633/634.
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January 2020 - Tothova lab welcomes Florence VerbeekWe are thrilled to welcome Florence Verbeek as a visiting graduate student from the University of Amsterdam, Netherlands. Florence is currently pursuing a medical degree as well as a masters degree in Biomedical Sciences. She has previously studied drug resistance in gastrointestinal malignancies. Her work in the lab will focus on therapeutic targeting of cohesin-mutant MDS and AML. Outside of the lab, she is an avid CrossFitter, and enjoys reading and watching reruns of The Office.
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December 2019 - ASH annual meetingMounica Vallurupalli presented the first oral presentation of the Tothova lab at the 2019 annual meeting of the American Society of Hematology in Orlando, FL. She discussed the development of new mouse models of cohesin-mutant myeloid disease and the preclinical studies with the PARP inhibitor talazoparib leading to a Phase 1b clinical trial of talazoparib in cohesin-mutant MDS/AML patients.
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November 2019 - Tothova lab welcomes Han LinWe are very excited to welcome Han Lin, PhD, a new postdoctoral fellow in the lab. Han Lin is joining our lab from the Cancer Science Institute of Singapore/National University of Singapore where she recently completed her PhD in Dr. Phil Koeffler’s lab. Her doctoral work was focused on understanding the function of ARID1A, a component of the SWI/SNF chromatin remodeling complex, in normal hematopoietic development. Welcome, Han Lin!
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September 2019 - Tothova lab welcomes Karin GolanWe are thrilled to welcome Karin Golan, PhD, a new postdoctoral fellow in the lab. Karin is joining our lab from the Weizmann Institute where she did her PhD with Tsvee Lapidot studying different aspects of basic hematopoietic stem cell biology, including the influence of light and darkness, mitochondrial transfer with bone marrow environment and the role of sphingosine 1-phosphate in HSC motility. Welcome, Karin!
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May 2019 - Tothova lab welcomes Ben MaronToday, we welcome Ben Maron to our lab. Ben is a rising junior at Williams College majoring in biology and mathematics, and a recipient of the Williams-Whitehead fellowship for the summer. He will be working on understanding the effect of cohesin complex mutations on nascent transcription.
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September 2018 - The Jimmy Fund Walk
The Tothova lab and friends team participated in the Jimmy Fund Walk celebrating its 30th anniversary on a beautiful first day of fall. We joined thousands of patients, families and care givers to walk 13.1 mile half marathon route from Wellesley to Boylston Street.
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August 2018 - Farewell to AnastasiaToday, we said goodbye to our fabulous summer student, Anastasia Tishena. She will be missed most for her mastery of the CellTiter-Glo assay as well as her wit in lab. Anastasia leaves us to start her junior year at Williams College. Click below to see some more photos of Anastasia's summer in the Tothova Lab.
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July 2018 - Farewell to KikiTo celebrate Kiki's last day in the Tothova and Ebert labs, we all set off to the Arboretum for a picnic! Kiki leaves the lab after two years. She is now off pursuing a Masters of Nutrition Science & Policy at Tufts University. We are all sad to see her go, but happy to know she'll be in Boston for the time being! Click below to see some photos from her farewell picnic.
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July 1, 2018 - Tothova Lab welcomes Anastasia TishenaToday, we also welcomed Anastasia to the Tothova Lab. Anastasia will be joining the lab for the next 10 weeks working on drug synergy experiments in various leukemia cell lines. Anastasia is joining us from Williams College, where she just finished up her sophomore year as a biology major and biochemistry concentrator.
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July 1, 2018 - Tothova Lab welcomes Mounica VallurupalliOn its opening day, the Tothova Lab welcomes its first postdoc, Mounica Vallurupalli. She joins us from Dana Farber, where she is a clinical fellow in hematology-oncology. In the lab she will be studying the role of epigenetic alterations, including in the cohesin complex, in the development of leukemia as well as in mediating response and resistance to therapy.
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July 1, 2018 - Tothova Lab Opens!July 1st marks the opening of the Tothova Lab. We are excited to open our lab at the Broad Institute, studying the epigenetic changes that contribute to various myeloid malignancies.
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