Harvard Medical School/MIT Health Sciences and Technology, M.D.
Brigham and Women's Hospital, residency in internal medicine
Dana-Farber/Partners CancerCare, fellowship in hematology and oncology
Broad Institute, postdoctoral fellowship
Zuzana Tothova, MD PhD
Dr. Tothova is an Assistant Professor at Harvard Medical School, Investigator in the Department of Medical Oncology and the Division of Hematologic Neoplasia at the Dana-Farber Cancer Institute, Associate Member of the Broad Institute, and principal faculty in the Harvard Stem Cell Institute. Dr. Tothova received her B.A. in Biology and Chemistry from Williams College, where she first developed her interest in cancer biology while studying the mechanisms of exit from mitosis in yeast in Dr. Wendy Raymond’s laboratory. She subsequently received a doctorate in Genetics from Harvard University for her work on FoxO transcription factors in self-renewal mechanisms of hematopoietic stem cells in Dr. Gary Gilliland’s laboratory, and an M.D. from Harvard Medical School/MIT in the Health Sciences and Technology program. She completed residency training in internal medicine at the Brigham and Women's Hospital and fellowship training in adult hematology and oncology at the Dana-Farber Cancer Institute and MGH Cancer Center. Dr. Tothova carried out her postdoctoral work in Dr. Benjamin Ebert’s laboratory at the Broad Institute where she developed new models of clonal hematopoiesis of indeterminate potential and myeloid neoplasms using multiplex CRISPR engineering of primary human hematopoietic stem cells and developed her interests in epigenetics of myeloid malignancies.
Dr. Tothova’s independent laboratory has focused on understanding the biology and therapeutic targeting of cohesin-mutant myeloid malignancies and basic mechanisms of chromatin regulation during MDS development. Dr. Tothova's work has been recognized by multiple awards, including the Paragon award for research excellence from the Doris Duke Charitable Foundation. She runs an NIH/R01-funded laboratory and attends on the inpatient leukemia service at the BWH. Dr. Tothova is also a recipient of multiple foundation grants from the American Society of Hematology, Leukemia and Lymphoma Society, Burroughs Wellcome Fund, Doris Duke charitable Foundation, Edward P. Evans Foundation, Gabrielle’s Angel Foundation, V Founda-tion, and the RUNX1 Foundation/Alex's Lemonade Stand. Outside of the lab, she is an avid foodie, skier, and an outdoors fan, enjoys art and classical music, and loves spending quality time with her husband, three kids, and Hamilton, their cat.
